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Availability of data and materials Datasets supporting the conclusions of this article are available in the TCGA database ( ICGC database ( HCCDB database ( and scAtlasLC database ( All raw and processed data are available from the corresponding author upon reasonable request

FSH, LH, and estradiol were all relatively low at baseline, reflecting the hypogonadal state of the participants

DOI: 10.3390/molecules28020656 67

Ascorbic acid enhances Tet-mediated 5-methylcytosine oxidation and promotes DNA demethylation in mammals

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