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Full disclaimer 1.Ipamorelin is a synthetic pentapeptide growth hormone secretagogue that selectively stimulates GH release from the pituitary by activating the ghrelin receptor (GHSR)

In this section, we review key findings from different surgical contexts: cardiac surgery (often involving global ischemia and extracorporeal circulation), neurosurgery (with focus on brain inflammation and cognitive outcomes), and abdominal surgeries involving liver and kidney ischemia (such as transplant or major resections)