The Phase 2 trial focused on adults with obesity or overweight with at least one weight-related condition
These, and other drugs in the pipeline, could provide alternatives to people who have tried diet and exercise and it has not been effective
(Published, July 2021) Pragya Sharma-Ghimire, Samuel Buchanan, Michael G
Sulfonamide Analogs To discover new DPP-4 inhibitors, Sharma and Soman developed a series of DPP-4 inhibitors containing various sulfonamide-pyrrolidine/piperidine scaffolds, assessing their binding affinities for the enzyme in comparison to Vildagliptin using in silico research
This demonstrates that month one is just the beginning
Liver disease may be one of the next major frontiers, with growing evidence that incretin-based therapies can improve MASH resolution and fibrosis-related endpoints