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The study proved that combination therapy (60 mg duloxetine + 300 mg pregabalin) was not significantly more effective than high-dose monotherapy (either 120 mg duloxetine or 600 mg pregabalin) in reducing pain after 8 weeks of intensified treatment

The number community and vendor sources reference most is roughly 500 mcg to 1 mg once daily, with a broader cited range of about 100 mcg to 2 mg per day

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The label recommends blood-sugar monitoring before and during use