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34,35,37,38 Other incretin therapies, such as activation of the gastric inhibitory polypeptide receptor (GIPR), have not been thoroughly studied in the kidney, consistent with a lack of detectable kidney GIPR expression 39

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[9] [10] This extended half-life means semaglutide accumulates gradually in your system over several weeks before reaching steady-state concentrations (typically 4-5 weeks)

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