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Other serious side effects include: Nausea Pancreatitis Risk of thyroid tumours or thyroid cancer Diabetic retinopathy (damage to your eyes thats caused by diabetes) Hypoglycaemia (low blood sugar) Gallbladder disease Allergic reaction

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Mechanistically, melatonin modulates mitochondrial metabolism, promotes mitochondrial fusion and maintains mitochondrial oxidative stress by altering autophagy to protect against mitochondrial injury

Highly processed or high-fat foods may worsen gastrointestinal side effects, especially early in treatment

Persistent Vomiting: Constant vomiting can lead to severe dehydration and esophageal damage

Bonser, L