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it produces a shorter GH pulse and is usually discussed separately from CJC-1295 with DAC

2 years and older with pro-opiomelanocortin (POMC), proprotein convertase subtilisin/kexin type 1 (PCSK1), or leptin receptor (LEPR) deficiency confirmed by an genetic test demonstrating variants in POMC, PCSK1, or LEPRgenes that are interpreted as pathogenic, likely pathogenic, or of uncertain significance (VUS)

1994 May-Jun;26(3):155-9

doi: 10.1038/s41579-018-0036-x 105 MeiniS.LaureanoR.FaniL.TasciniC.GalanoA.AntonelliA.et al

The first of a series of CVOT was the ELIXA trial, which compared patients with T2D and a history of a heart attack or unstable angina to either receive once daily injections of lixisenatide or placebo

[cited 2025 Nov 20]