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Finally, as a proof-of-concept study, we bioisosterically replace the naphthyl ring of utrophin modulator ezutromid, with a range of aryl-fused BCHeps, and demonstrate the retainment of bioactivity while improving metabolic stability to CYP enzymes
doi: 10.1007/s00438-018-1517-3 34 MrowickaMagorzataMrowickiJDraganGMajsterekI
(The fourth peptideMOTs-Creceived a seven-to-five vote in favor, with two abstentions.) The advisory panel, which includes several members tied to peptide-related businesses and telehealth clinics, will consider three more peptides on Friday
10.1093/jac/dks296 J
