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Alpha Lipoic Acid and Vitamin E provide antioxidant support, reducing oxidative nerve damage

The patient group was selected as having both relatively reduced serum UA and imaging evidence of dopaminergic deficits without yet requiring dopaminergic therapy

Matsuzaki, J

515 Preliminary data have shown that the pharmacological effects of IGF-1 affect synaptic development primarily by modulating the MAPK and mTOR pathways, as validated in PhelanMcDermid syndrome and Rett syndrome

Notably, the researchers did not observe any change in melatonin levels in young monkeys who were given the same treatment [7]

2021;9(3):e14739