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J., Farr, A

2022 Oct 13;20(4):15593258221126827

Primarily, it is logical to consider caspase-8 as a possible molecular switch that determines the plasticity of cell death pathways in mature erythrocytes, since caspase-8 is a well-known cell fate-determining enzyme, regulating apoptosis, necroptosis, or pyroptosis depending on its own activation status and interactions with other components of the cell death machinery [129, 209]

Can't tell it is old in any way, shape, or form, even when it had been opened and used

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Participants were required to be enrolled for at least one year in the health system prior to the index date to have baseline information