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Instead of aiming at inhibition or modulation of the traditional targets of antibiotics, attempts are being made to identify pathways necessary for the microbes virulence (i.e., ability to cause a disease or damage) and the pathogenesis (how the infection develops to a disease) [71]

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Matsunaga T, Sano H, Takita K, Morita M, Yamanaka S, Ichikawa T, et al

Genetic variation in choline-metabolizing enzymes alters choline metabolism in young women consuming choline intakes meeting current recommendations

Cellular effects measured over months

The results showed that the proportion of SA--gal positive cells after OGD treatment was significantly higher than that in the control group (Figure 3D)