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The proposed mechanisms range from well-validated (FDA-approved GLP-1 agonists for weight loss) to highly speculative (epitalon, thymosin alpha-1, MOTS-c) with limited or no human clinical validation

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The condition is strongly linked to metabolic issues, as an estimated 35% to 80% of patients experience insulin resistance

Niacinamide Niacinamide is a form of vitamin B3 that plays an important role in cell metabolism

The data showed two times more cases of macular degeneration in the GLP-1 patients

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