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High-dose intravenous protocols (up to 50 mg/kg daily, ~3,500 mg for a 70 kg person) have been used safely in patients with metabolic disorders [8] , indicating a wide therapeutic margin
doi: 10.19852/j.cnki.jtcm.2023.04.002 96 El-TedawyDMAbd-AlhaseebMMHelmyMWGhoneimAI
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However, some women experience disrupted sleep during dose escalation phases, particularly if nausea or digestive discomfort interferes with nighttime rest
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