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That window has been compressed to 6 months

doi: 10.1111/brv.13135, 58 JuJ.ZhangH.LinM.YanZ.AnL.CaoZ.et al

Disruption in this pathway, including mutations in key genes or dysregulation of associated proteins, can lead to various pathological conditions

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Additionally, although a continuous value of serum GPX-3 concentration did not show significant predictive potential for poor outcomes, we wondered whether a categorical value of serum GPX-3 concentration according to its cut-offs of poor outcomes such as all-cause mortality, ESKD, CVA, and ACS could be a significant predictor of those poor outcomes