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4.1.15 Supernumerary limbs (slmb) and -TrCP1 and -TrCP2 The Drosophila Cullin-RING E3 ligase component slmb, encoded by slmb , and its mammalian orthologs -TrCP1 and -TrCP2 (F-box proteins within the SCF complex) are critical regulators of circadian timing through their control of per and tim protein stability (Grima et al., 2002

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[DOI] [PMC free article] [PubMed] [Google Scholar] 173.Alshabanah O.A., Hafez M.M., Al-Harbi M.M., Hassan Z.K., Al Rejaie S.S., Asiri Y.A., Sayed-Ahmed M.M

So, as well as offering protection, it also helps with regeneration