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This results from a tyramine-induced depletion of norepinephrine normally present in the readily releasable vesicle pool, and replacement of vesicular norepinephrine with tyramine (which functions as a false- or pseudo- neurotransmitter), which when released has no effect on postsynaptic adrenergic receptors (Figure 1)

[11] Ozempic should never be considered a replacement for evidence-based cholesterol therapy when such treatment is clinically indicated

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hs-CRP: A marker of total body inflammation