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It should not be bought online or used outside an authorised clinical trial
it does not imply medical superiority
GLP-1 stands for glucagon-like peptide-1
Extend your current dose step if: Nausea persists beyond 10 days at the current dose You are experiencing vomiting more than twice per week Diarrhea is disrupting daily activities You have lost significant amounts of food intake due to GI symptoms Your quality of life is substantially affected Stay at the current dose for an additional 2 to 4 weeks, then attempt the escalation again
Common injection sites used in trials include: The abdomen (at least 5 cm away from the navel) The upper thigh The upper arm (outer aspect) Rotating injection sites with each weekly dose is recommended to reduce the risk of localised skin reactions such as bruising or injection site discomfort
While body weight and metabolic phenotypes remain the primary endpoints, the outcome spectrum is progressively extending toward lipotoxic load [e.g., hepatic fat and visceral adipose tissue (VAT)], inflammatory/cardiometabolic risk markers, and reproductive outcomes with higher clinical decision-making value, such as menstruation, ovulation, and pregnancy
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