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The peptide may also suit people who have tried semaglutide or other GLP-1 agonists and cannot tolerate the gastrointestinal side effects

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Some of the medications will need adjustment in subsequent months

Tirzepatide, as an FDA-approved compound with a well-characterised safety profile, remains the more accessible and better-understood option for dual-pathway metabolic research

If you cannot tolerate the side effects from recommended doses, sticking with the smaller dosage can be a solution, he says