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It is worth noting that for elderly people who are not obese or on the verge of sarcopenia, excessive weight loss may accelerate the progression of sarcopenia and increase the risk of falls and poor prognosis

While hypoperfusion likely plays a role, oxidative stress and subsequent renal tissue damage from reactive oxygen species occurs due to both ischemia-reperfusion injury and activation of inflammatory cascades when blood is exposed to the CPB circuit [37]