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In chronic hemodialysis patients, NAC administration has been shown to decrease circulating homocysteine levels [50,51] as well as decrease other inflammatory markers, including asymmetric dimethylarginine and malondialdehyde

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Although large and flat PPI interfaces may be more conducive to peptide and protein drug targeting, 75,583,584 small molecule inhibitors also play a role in some AD-related PPIs due to their unique advantages

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