We declare that there are no conflicts of interest between any of the authors and the commissioned production company of Prodom, namely, Zunyi Lexi Medical Products Co., LTD., and the project funding department
Conclusion NPT1, NPT4, ABCG2 expressed on the apical membrane and OAT1, OAT3 expressed on the basolateral membrane have been confirmed to contribute to the secretory transport of urate from proximal tubular epithelial cells into the tubule lumen (Wen et al., 2020)
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The safest approach is increasing potassium through food sources first, then supplementing conservatively if needed, always under medical guidance
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