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Irreversibility tends to be associated with more than 6 months of therapeutic delay, but its variability is unexplained

The mechanism might involve direct antiemetic effects of B12, or it might reflect improved overall metabolic function when vitamin status is maintained

and 3) abnormal fat (stubborn fat that is locked away, usually in abdomen or hips.)

(Hematological and other disorders as causes)

For most people, daily oral methylcobalamin is more practical than chasing B12 energy shots, which are really designed for confirmed deficiency or malabsorption

Conservative avoidance deserves serious consideration in this group