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Esto podra indicar que si bien hay percepciones positivas hasta ahora, existe cierta incertidumbre sobre la efectividad mxima alcanzable con el tiempo

Interestingly, patients with higher percentages of GI AE were more likely to achieve greater weight loss

The FDA has approved Qsymia (phentermine and topiramate) in children aged 12 years and older whose BMI is at the 95th percentile or higher, standardized for age and gender

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Although the study did not distinguish the efficacy among different heterozygous LMP variants, it confirmed that heterozygous mutations in the LMP pathway (including MC4R ) are associated with compromised long-term surgical outcomes, consistent with the findings in heterozygous MC4R P/LP variant carriers