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Tirzepatide reduces visceral fat through two parallel mechanisms: it slows gastric emptying and increases satiety signals (via GLP-1 activation), while simultaneously improving insulin sensitivity and promoting fat cell death (via GIP activation)

PMID: 29879879

When you lose weight, your body burns fat everywhere, including the face, so cheeks can flatten, skin can loosen, and fine lines can look more obvious

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Results depend on skin type and lifestyle, but are described by most patients as reversing the clock on sun damage and fatigue