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Pradeep, , Kaur, P., Bempong, P., Lillard, S., Asea, A

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Additionally, clinical trials involving hypertensive patients have shown that Pycnogenol supplementation can significantly lower blood pressure and reduce blood concentrations of the potent vasoconstrictor endothelin-1, allowing a substantial percentage of patients to safely reduce their dosage of prescription calcium channel blockers under medical supervision

The differential outcomes observed in Figure 3 suggest that the anxiolytic efficacy of the treatments hinges on their specific molecular configurations and the mechanisms by which they modulate neurobiological pathways