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the cells were subsequently placed in an incubator for 20 min at 37 C

In adults, glucuronidation and sulfation play a major role in APAP metabolism, and approximately 5% of the substrate is converted into NAPQI (Court et al., 2001

This suggested DSIP might modulate pain processing through mechanisms distinct from classical opioid pathways

Oral administration of glutathione alone is thought to be ineffective for altering glutathione levels due to hydrolysis during digestion and poor absorption