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Pathway 2 - Insulin Sensitivity at Two Layers Both compounds improve insulin signaling, but at different layers

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Paired with a strong GLP-1 agonism that counters its hyperglycemic effect via insulin secretion, the glucagon arm becomes an accelerator of energy expenditure and lipid catabolism particularly relevant for hepatic steatosis

This is why many experienced lifters intentionally stay in the 4-8mg range rather than pushing to maximum doses

3A), but a significant interaction between time and group was not observed