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With newer, longer-acting, and more potent GLP-1RAs increasingly taking over the scene in the treatment of type 2 diabetes and, as of recently, also obesity, it is obvious to speculate whether these compounds would be preferable in the treatment of BAD

Semaglutide (Wegovy) recently became the first GLP-1 approved by the FDA to treat adults with MASH with moderate-to-advanced fibrosis, based on the phase 3 ESSENCE trial

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To our surprise we discovered that only a single GCG encodes a GLP-1 peptide with two functions, one in venom and the other in the gut

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