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Theres a very high probability that they do and this is particularly concerning for most of the people that will be reading my blog, because, spoiler alert, its pretty much all about thyroid-related problems
The GRADE approach assessed the quality of the evidence for each outcome across five domains: risk of bias, inconsistency, indirectness, imprecision and publication bias
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303 Interestingly, intracerebroventricular administration of GLP-1 did not inhibit feeding in GLP-1R knockout mice but did in wild-type mice, suggesting that GLP-1R signalling mediates satiety, although no evidence for abnormal body weight or feeding behaviour was reported in GLP-1R knockout mice
Nathan DM, Lachin JM, Bebu I, Burch HB, Buse JB, Cherrington AL, Fortmann SP, Green JB, Kahn SE, Kirkman MS, Krause-Steinrauf H, Larkin ME, Phillips LS, Pop-Busui R, Steffes M, Tiktin M, Tripputi M, Wexler DJ, Younes N
