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GH stimulation may theoretically encourage tumor growth, so this therapy is avoided in anyone with an active malignancy or a history of cancer that is not in complete remission

For anyone outside a laboratory, the same fragmentation creates obvious consumer-protection concerns

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In response to the FDAs complete response letter (CRL), announced Friday by Mesoblast, the New Yorkbased biopharma will conduct a targeted, controlled study in the highest-risk adults with the greatest mortality. Mesoblast noted that the adult study is in line with its overall commercial strategy, which involves a progression from pediatric to adult SR-aGVHD indications

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