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While some vitamins last just a few days, others, like vitamin D, can stay in the system for months
Cancer and Metastasis Reviews , 11 (34), 227235
Recent studies with animal models provide evidence that pheomelanin pigment pathway is implicated in UV radiation-independent carcinogenic contributions to melanomagenesis by mechanisms of oxidative damage 6,7,8 Two non-exclusive hypotheses were proposed to define pheomelanins pro-oxidant activity: (i) the pigment promotes the formation of damaging ROS and (ii) the pigment depletes protective antioxidants (e.g., glutathione) 9,10
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Thus, LC not only improves the GSH status, which enables the upregulation of vitamin D regulatory genes, but also reduces the TNF- levels and adds to VDR/PGC-1/GLUT4 activation
