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Notably, our lead compound KL1 reduced ROS/RNS production in macrophages, sensitized intracellular persisters to antibiotics, and enhanced antibiotic efficacy in murine infection models

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GSH deficiency as evidenced by a decrease in the GSH/GSSG ratio manifests itself largely through an increased susceptibility to oxidative stress, and the resulting damage is thought to be involved in SARS-CoV-2 infection leading to COVID-19 disease (39, 4353)

Franzn, S., Pihl, L., Khan, N., Gustafsson, H