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In clinical trials, participants lost an average of 14.9% of their body weight over 68 weeks (published in the New England Journal of Medicine)

For some patients, the injection site may irritate, but these symptoms are usually minor

This effect is particularly enhanced when used in conjunction with weight loss programs, such as Intermittent Fasting (IF) or regular exercise, yielding even better results

However, they also dont last as long, so the medication must be taken daily instead of weekly to maintain the drugs effects

The SELECT trial result - 20% reduction in major cardiovascular events with weekly semaglutide 2.4mg in adults with established cardiovascular disease plus overweight/obesity - was the first time a weight-loss medication demonstrated cardiovascular outcome benefits in a major randomized controlled trial

Single-cell transcriptomics of the human endocrine pancreas