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The predicted Day 5 nirmatrelvir exposure parameters in adult subjects with mild-to-moderate COVID-19 who were treated with PAXLOVID in EPIC-HR are presented in Table 4

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Treatment of rats with Ile-thiazolidide inhibited DPP4 activity, improved oral glucose tolerance, and enhanced the insulin response to glucose, findings consistent with the potentiation of endogenous GLP-1 and GIP activity in vivo (143)

Nutrients 16:182

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