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Tsuneoka Y, Nishimura T, Oka JI

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While the freezing behavior may confound the measurement of acute nociceptive responses measured using classical reflex-based assays, our data from the CPP assay, which assesses the affective-motivational component of pain without relying on motor reflexes, provide additional support for the role of APC GABA neurons in analgesia, particularly within the affective dimension of pain

And in the world of scientific research, clarity and reproducibility are the ultimate goals

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