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This treatment is based on science, not myth

296,298 One case report described the benefit of SAMe in a 32 year old patient with anxiety who was found to have a MTHFR gene mutation: treatment with methylated B 12 and folate was not effective for relieving symptoms until SAMe, 400 mg twice daily, was added

With the HoMEso applicator Use the HoMEso applicator only as directed, at the gentle depth used across the HoMEso system

If this happens, simply drink a glass of Optimal Electrolyte, and increase the amount of Bile Nutrients you take

Doses of 300600mg are typical

However, combined efficacy and safety have only been examined in preclinical models, not in controlled human trials, so any pairing exists strictly within Research Use Only parameters