semaglutide 1.25 mg Wegovy Pill: First Oral GLP-1 for Weight Loss (2025) What to Know About Semaglutide:

There is also some limited evidence suggesting that individuals who carry certain polymorphisms in genes involved in vitamin C transport and detoxification mechanisms may have lower plasma vitamin C concentrations even with high vitamin C intakes (see also Vascular complications of diabetes mellitus) (reviewed in 27)

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The oral formulation, approved in 2019, represented the first oral option in this drug class

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Side Effects Both forms of semaglutide can cause side effects, most commonly gastrointestinal issues like nausea, vomiting, and abdominal pain