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US chronic disease management companies, Lark and Virta, both having raised funds in excess of $200m, are conspicuous in their absence, the latter in particular continuing to emphasise nutrition, lifestyle interventions, and de prescribing

Messiah, who is also a Professor of Pediatrics and Director of the UTSW Child and Adolescent Population Health Program

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Mazdutide's potential advantages lie in its glucagon component, which directly targets hepatic steatosis and may prove particularly valuable for patients with MASH or metabolic liver disease

Raval et al., 2020