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Both omeprazole and esomeprazole inhibit CYP2C19, leading to: Reduced formation of active clopidogrel metabolite Decreased antiplatelet efficacy Increased risk of thrombotic events (MI, stroke, stent thrombosis) Clinical takeaway: When gastric protection is required in patients on clopidogrel, consider safer alternatives such as: Pantoprazole Rabeprazole This simple switch can significantly improve therapeutic outcomes and patient safety

The expiration date is determined based on stability studies and represents the latest date at which the product's safety and efficacy can be guaranteed

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Poor quality or contaminated products can lead to adverse effects