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Prescribing information (AstraZeneca Pharmaceuticals, 2025)

However, more large-scale randomized controlled trials (RCTs) are required to verify the neuroprotective effects of metformin

It covers more pathways than CagriSema (which is missing GIP) but fewer than cag + retatrutide (which adds glucagon)

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A consistent routine will also help you to set your body up for optimal weight management in the future when you have completed your GLP-1 journey