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GLP has been discussing the potential offering with advisers including Citi and Morgan Stanley, said one of the sources and a third separate person with knowledge of the matter

The potential mechanisms were found to be related to regulating neurotransmitter (5-Hydroxytryptamine) and inflammatory factor levels, and importantly, blocking the JAK2/STAT3 signaling pathway effectively alleviated depressive symptoms in BC combined with depression mice, inhibiting tumor progression (Kumar and Roy, 2023)

Pregnancy and breastfeeding warrant avoidance due to insufficient safety data in these populations

Vitamin B6 therapy should be started as early as possible in this group of patients, as prompt and timely treatment is strongly associated with a favorable prognosis