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Rapamycin's safety in MCI is currently being evaluated in a Phase I trial (NCT04200911), but the translational hurdle determining whether the medication can continue to engage its targets once neurodegeneration reaches a late-stage plateauremains (236, 237)

Please note: this article focuses on the benefits of adding B12 vitamins as supportive care to the main FIP treatment

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doi: 10.1016/j.clinthera.2008.08.006 52 BuseJBHenryRRHanJKimDDFinemanMSBaronADet al

The effect was comparable to that of ibuprofen and was safer (47)

Preclinical investigations indicate that the combined peptides may affect early wound responses by supporting cellular organization, directional movement, and adaptive signaling within experimentally injured tissue environments (3,20)