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While additional research is required, IGF-1 LR3 may help understand the molecular underpinnings of metabolic function in various cellular systems

Endocrine, 2025: pp

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Candidate polymorphisms in this context include cSHMT -C1420T, a common gene variant in cSHMT which results in an amino acid substitution that prevents the multienzyme complex from undergoing localization to the nucleus