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During the first 36 weeks of the trial, patients lost, on average, about 20% of their body weight

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These features may suggest complications or alternative diagnoses requiring investigation

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They may include: Upper respiratory tract infection symptoms, such as sore throat or stuffy nose Painful urination Headache Swelling in the hands or feet Other side effects, which are less common but might be more severe, could include: Severe joint pain Heart problems, such as shortness of breath or unusual tiredness Burning sensation during urination Tell your doctor if you notice any of these side effects