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Follistatin: Myostatin inhibitor promoting muscle growth

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Human Fis1 directly interacts with Drp1 in an evolutionarily conserved manner to promote mitochondrial fission

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J Appl Physiol (1985) 121:730-40 (2016)

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REDEFINE-1 (NEJM 2024, n=3417, 68 weeks): CagriSema (cagrilintide 2.4 mg + semaglutide 2.4 mg) 22.7% weight loss (ozempic 2.4 mg 16.1%)

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