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This distinction becomes clinically relevant for anyone with MASLD, elevated liver enzymes, or metabolic syndrome components beyond obesity

I've seen clients walk in with dull, uneven complexions and walk out (after a few sessions) with that coveted "glow from within" look

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For example, Lactobacillus johnsonii reduces circulating KYN and intestinal IDO activity in rats [185], Bifidobacterium infantis increases plasma TRP and KYNA in male rats [186], and probiotic supplementation in humans lowers plasma KYN while increasing TRP levels [187]