Respect the 4-week cycle limit unless a physician specifically prescribes otherwise
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Because it is the only free variable, it sets the concentration and the measurement resolution for everything that follows
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In less deficient areas, repeat dose every 5 - 6 months or as necessary
On the physical side, you might notice constant tiredness that doesn't improve with rest, heavy legs during workouts, shortness of breath on efforts that shouldn't wind you, pale skin, and a need for frequent napping