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Clinical trials have focused on people living with obesity, early research shows it could, if licensed, be used for conditions like type 2 diabetes and fatty liver disease

How the calculator works The calculator uses a cubic Hermite spline model fitted to published clinical trial data

Storm FK, Eilber FR, Mirra J, Morton DL

Fact: Skin lightening is a side effect of extremely high doses

The most common adverse effects are mild gastrointestinal symptoms (nausea, vomiting, diarrhea) that typically occur at rates similar to placebo in controlled trials

For a niche, trial-and-error category like histamine intolerance, that long runway is a real advantage