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In contrast, the main difference of damage-associated molecular patterns is that they recognize endogenous molecular structures associated with damaged cells

Molecules such as fibroblast growth factor 21 (47), BCL2 interacting protein 3/NIP3-like protein X (48) and acteoside (via the NRF2-mitophagy axis) (49) mitigate ferroptosis by restoring mitochondrial function or removing damaged mitochondria, underscoring the protective role of mitophagy against ferroptosis

Utilizing stirring, sonication, or boths combinations are the most usual methods