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Evidence revealed that endogenous and exogenous IGF-1 administration protects against the onset and progression of diabetic cardiomyopathy [278, 279]

While theyre not magic bullets, they could become helpful tools when used as part of a broader, personalized plan

Patients who come in with a longevity or health-span focus rather than a specific metabolic complaint tend to respond better to NAD+ as a primary intervention

(n = 4 mice for eGFP control and n = 5 for A51 OE mice)

doi: 10.23876/j.krcp.22.001 31 KarakasisPKoufakisTPatouliasDBarkasFKlisicAMitrovicMet al

Brain Regions Involved: GLP-1 receptors are found in key areas like the ventral tegmental area (VTA) and nucleus accumbens (NAc), which are central to the brain's reward pathways